mpobiz wrote:masukuma wrote:mpobiz wrote:masukuma wrote:it's a rather stable virus that doesn't mutate often - however, the longer it stays in a population... the more the chances that a new strain will spring up... I think we have gone over this before. The bad thing is that natural immunity to an earlier strain does not guarantee immunity to a new strain! The immune system is an interesting thing - it basically works on proteins on the virus that it has never seen before. The virus is like 30,000 bases long and it may build an immunoresponse on a random protein that may change due to the mutation without affecting the nature of the virus and thus the virus from the second strain will not be recognized by the body. that's why the vaccines are better - they are pinpointed to attack something that if changed will change the nature of the virus.. the S-spike protein.
First you should tell people that there is nothing like immunity when it comes to any disease. It's only that when you get infected you get very mild or no symptoms. But you still get infected. The infection also fades away very quickly. The term immunty is relative
Yes - the outcome of an immune response should be viewed on a continuum of severity of symptoms. Infection will always occur (a pathogen getting into your body) but the severity of symptoms is a product of how fast your body responds with an appropriate response to the infection. The longer it takes - the more the time to develop symptoms. Vaccinations shorten that time so as to ensure that the body does it once with a fake viral protein and remembers this response when the real thing comes around.
The load of the pathogen is another factor. A small amount of virus will take a while before it replicates to critical mass in order to affect the body. During this time the body is mounting a response and thus it can be that asymptomatic cases are scenarios where the viral load was so little that by the time the body was launching an immune response - the viruses were not in such a state that they can cause damage.
Then it's safe to say that the natural "immunity" that worked on the first strain will do its magic again.
What I can say is we are even safer when we encounter more strains. This drastically improves and buffers the immune system. This can be genetically passed to the comming generation.
A small study was curried out where it was seen that a generation of children borne of parents with HIV developed immunity.
No it's not safe to say that....
1) We don't get to chose what strain is created. could the strain be more infectious (spreads around faster or deadly... kills more?) - we don't get to chose that. Remember - at one time there was no Covid and then a whole year went down the drain. This whole year people have been relying on Natural immunity. Which is a crude weapon. it's effective against what it knows but not what it does not know. I have a friend who tested positive for antibodies earlier and then had a worse case of Covid later - he did survive.. yes but the suffering was worse the second time over... was it a newer strain? I don't know. Vaccines are designed to be precise and focus on the characteristic of the virus that won't change without rendering it "not covid". the spike protein. can the body focus on the s-protein itself... it's possible but it can also focus on the proteins created by the rest of the 30,000 bases that make up the virus' RNA.
2) genetics are not as easy to determine. Your immunity is not passed on! it's not genetic. it's a thing that happens to your other cells. the change MUST TAKE PLACE IN THE GONADS. That means that the cells in your balls must mutate in a way to pass on the immunity to your children. It's not in your control. That's why children don't inherit resistance to ENT diseases from their parents... they build their own over time. by age 7 they are set. No grown-up complains of ear infections but their children will get ENT infections. Is immunity/resistance to HIV a factor of how long the virus stays in the body? Maybe! since it stays with you through your life... do your gonads get infected with it... yes! it's the primary way of spreading. does it happen that over years and years of living with this do your gonads get to release strands that have a mutation that is resistant to this disease? I can see how... but not with a disease that takes at most 37 days to reduce the viral load undetectable levels.
Can we adapt eventually to have a genetic response to this... I guess! Can our immune response eventually beat this bastard? Yes, but what's easier... getting a shot that any negative outcomes (if any) are visible in the first 48 hours or roll the dice like a caveman and see what happens? I chose the shot.
All Mushrooms are edible! Some Mushroom are only edible ONCE!